HERE'S MONDAY'S HEADLINES PLUS 169 MORE ARTICLES & STUDIES FOR YOU THAT WE POSTED IN THE LAST 8 DAYS! MORE MS NEWS THAN ANY SITE IN THE WORLD!

 Rituximab review

IMPAIRED DECISION-MAKING AND DIFFUSION ORIENTATIONAL COMPLEXITY IN PEOPLE WITH MULTIPLE SCLEROSIS

Vitamin d: shining a light on clinical and sex specific effects in multiple sclerosis?

The relation between Vitamin D status with fatigue and depressive symptoms of multiple sclerosis.

Multiple Sclerosis Research: Chinese Medicine..Getting DMT is ...

 Mary Lahammer on living with multiple sclerosis: The feared disease a journalist lives with is no longer a death sentence.

Validity of the Dynamic Gait Index in People With Multiple Sclerosis

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 Longitudinal MR Imaging of Iron in Multiple Sclerosis: An Imaging Marker of Disease

Merck saw higher prices for its Rebif treatment for multiple sclerosis after it became available in a single-dose portable injector. 

Smoking and risk of treatment-induced neutralizing antibodies to interferon β-1a. The finding that current smokers have an increased risk of developing NAbs to IFNβ-1a has implications, both for the practical care and the treatment of MS; it also provides an interesting perspective of the lungs as an immune-reactive organ, reacting upon irritation.

 Tonsillectomy, Appendectomy Linked to Increased MS Risk

 Have MS Hospitalization Rates Declined?

 Clinical Advances in Relapsing-Remitting MS: The Role of Oral Disease-Modifying Therapies

Vitamin d3 concentration correlates with the severity of multiple sclerosis.

Retired Manchester police officer won't back down in battle with MS

Regional gray matter atrophy in multiple sclerosis causes neuropsychologcal problems

Immune competence after alemtuzumab treatment of multiple sclerosis

Hunting for autoantibodies in multiple sclerosis

Protein array-based profiling of CSF identifies RBPJ as an autoantigen in multiple sclerosis

Constructing an adaptive care model for the management of disease-related symptoms throughout the course of multiple sclerosis--performance improvement CME

Age-specific sex ratio of multiple sclerosis

 Dimethyl fumarate (BG-12) for the treatment of multiple sclerosis.

RESEARCHERS TEST POPULAR SPORTS SUPPLEMENT IN EFFORT TO IMPROVE LIFE FOR MS PATIENTS

Kelly Osbourne - Kelly Osbourne wishes she had MS instead of Jack

I discovered I had multiple sclerosis live on the radio! Radio presenter tried to ignore strange new symptoms until a concerned listener diagnosed her condition in a text message

l-Selectin is a possible biomarker for individual PML risk in natalizumab-treated MS patients
Open Thoracic Cordotomy as a Treatment Option for Severe, Debilitating Pain.

Hunting for autoantibodies in multiple sclerosis

Oropharyngeal dysphagia in patients with multiple sclerosis: do the disease classification scales reflect dysphagia severity?

1)H magnetic resonance spectroscopy in multiple sclerosis and related disorders.

Multiple Sclerosis in the Levant: A Regional Consensus Statement.

Regional gray matter atrophy in multiple sclerosis causes ...

Risk factors for rare diseases can be risky to define: PML and Tysabri/natalizumab

Age-specific sex ratio of multiple sclerosis

Constructing an adaptive care model for the management of disease-related symptoms throughout the course of multiple sclerosis--performance improvement CME.

Access to Multiple Sclerosis Specialty Care.

Assessment of changes in immune measures of multiple sclerosis patients treated with laquinimod.

Impaired decision-making and diffusion orientational complexity in people with multiple sclerosis.

Any role for probiotics in the therapy or prevention of autoimmune diseases? Up-to-date review. 

Laquinimod for multiple sclerosis.

COMPLICATIONS OF BACLOFEN PUMPS: In multiple sclerosis and spinal cord injury patients, intrathecal baclofen therapy has a complication rate of 1% per month. Complications are mainly due to catheter-related problems (74%). The intrathecal baclofen dosage stabilizes in the long term, indicating that long-term tolerance, defined as progressive diminution of the susceptibility to the effects of a drug, is not present.

Bone Marrow transplants. Non-myeloablative autologous haematopoietic stem cell transplantation expands regulatory cells and depletes IL-17 producing mucosal-associated invariant T cells in multiple sclerosis.Brain. 2013  [Epub ahead of print]

Multiple Sclerosis Diet: Doctor Terry Wahls Reverses MS With Diet Alone. Plus VIDEO: Minding Your Mitochondria: Dr. Terry Wahls at TEDxIowaCity

 This Company Is Tackling Multiple Sclerosis Head On

Hunting for autoantibodies in multiple sclerosis. 

But You Look Great! Jack Osbourne's 'Invisible' MS! Many multiple sclerosis symptoms are felt but not seen in celebrities like Jack Osbourne & Ann Romney

MS Patients' Quality of Life Is Lowest Regarding Personal Relationships, According to Survey

Modeling or Charity? CBS Investigates Allegations Against Midland Modeling Agency

Opexa Therapeutics, Inc. a biotechnology company developing Tcelna®, a patient-specific T-cell immunotherapy for the treatment of multiple sclerosis (MS), today announced the pricing of an underwritten public offering... 

The link between multiple sclerosis and sunlight

The trial is a randomized, placebo controlled, Phase Ib study in multiple sclerosis (MS) patients treated with Trophos' olesoxime as an add-on therapy to...

SATIVEX STUDY RESULTS

L-Selectin is a possible biomarker for individual PML risk in natalizumab-treated MS patients.

Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies.

Assessing humoral immunocompetence after alemtuzumab treatment in MS.

Immune competence after alemtuzumab treatment of multiple sclerosis. 

Longitudinal MR Imaging of Iron in Multiple Sclerosis: An Imaging Marker of Disease.

Multitasking in Multiple Sclerosis: Can it Inform Vocational Functioning?

Presence and significant determinants of cognitive impairment in a large sample of patients with multiple sclerosis.

Protein array-based profiling of CSF identifies RBPJ as an autoantigen in multiple sclerosis.

Surgical Outcomes of Trigeminal Neuralgia in Patients with Multiple Sclerosis.

MicroRNA Expression Changes during Interferon-Beta Treatment in the Peripheral Blood of Multiple Sclerosis Patients.

Therapeutic Decisions in Multiple Sclerosis: Moving Beyond Efficacy.

Coexistence of Multiple Sclerosis and Ankylosing Spondylitis: Report of Two Cases.

Doppler Ultrasound Examination of Multiple Sclerosis Patients and Control Participants: Inter-observer Agreement and Association with Disease.

SEROQUEL

ORAL SEROQUEL (Quetiapine Fumarate) for the Treatment of Multiple Sclerosis: Focus on Myelin Repair.

Pregnancy and perinatal outcomes among women with multiple sclerosis

Cannabis Not the Only Illicit Drug Linked to Schizophrenia

No Evidence for Impairment of Venous Hemodynamics in Children or Young Adults with Pediatric-Onset Multiple Sclerosis.
 
Retrograde retinal damage after acute optic tract lesion in MS.

Vitamin D: effects on childhood health and disease.

Genetic risk variants in African Americans with multiple sclerosis.

High dose thiamine improves fatigue in multiple sclerosis.

Imaging new lesions: Enhancing our understanding of multiple sclerosis pathogenesis.

Iron and neurodegeneration in the multiple sclerosis brain.

Magnetic resonance frequency shifts during acute MS lesion formation.

No evidence of a link between multiple sclerosis and the vaccine against the human papillomavirus.

Novel modulating effects of PKC family genes on the relationship between serum vitamin D and relapse in multiple sclerosis.

Randomized controlled pilot study of customized pamphlets to promote physical activity and symptom self-management in women with multiple sclerosis

Brain reserve and cognitive reserve in multiple sclerosis: What you've got and how you use it.

Disclosing a misdiagnosis of multiple sclerosis: do no harm?

Can somatosensory evoked potentials predict disease course in early multiple sclerosis patients?
Optic neuritis and the evaluation of visual impairment in multiple sclerosis.

Current and new directions in MRI in multiple sclerosis.

General health issues in multiple sclerosis: comorbidities, secondary conditions, and health behaviors.

Pediatric demyelinating diseases.

SOX17 is expressed in regenerating oligodendrocytes in experimental models of demyelination and in multiple sclerosis.

Patient management problem-preferred responses.

Special considerations when coding for patients with multiple sclerosis.

Multiple sclerosis treatment: risk mitigation.

Migraine Headaches And Pain With Neuropathic Characteristics: Comorbid Conditions In Patients With Multiple Sclerosis.

Spinal cord lesions and disability in Hispanics with multiple sclerosis.

Electropysiologic evaluation of the visual pathway in patients with multiple sclerosis.

Premature immune senescence in children with MS T-cell homeostasis in pediatric MS Strategies for protecting oligodendrocytes and enhancing remyelination in multiple sclerosis. Levofloxacin-Induced Delirium in a Patient Suffering from Schizoaffective Disorder and Multiple Sclerosis. Subclinical myocardial dysfunction in multiple sclerosis patients remotely treated with mitoxantrone: evidence of persistent diastolic dysfunction. Plasma osteopontin levels are associated with disease activity in the patients with multiple sclerosis and neuromyelitis optica.  Have MS Hospitalization Rates Declined? Have disease-modifying therapies for MS modified cost, hospitalization rate, or length of stay? Tysabri/Natalizumab: A Review of Its Use in the Management of Relapsing-Remitting Multiple Sclerosis. Aubigio (Teriflunomide) was recently approved for treatment of MS & has demonstrated clinical efficacy & safety in a number of large, multicenter, phase III clinical trials. Furthermore, existing clinical experience with its parent drug, leflunomide, provides indirect long-term safety data. This review summarizes teriflunomide's pharmacologic properties, pivotal clinical trials, and safety profile & ends with a discussion of the role of teriflunomide in the context of current and emerging MS treatment options. Can Multiple Sclerosis Be Treated Surgically?  T-cell homeostasis in pediatric multiple sclerosis: Old cells in young patients.http://www.ncbi.nlm.nih.gov/pubmed/23911752 Premature immune senescence in children with MS: Too young to go steady. MAPT Gene Rs1052553 Variant is not Associated with the Risk for Multiple Sclerosis  Siponimod for Relapsing-Remitting MS Recycled Meds and New Approaches in Multiple Sclerosis Active MS Is Associated With Accelerated Retinal Ganglion Cell/Inner Plexiform Layer Thinning Spinal cord lesions and disability in Hispanics with multiple sclerosis.  How Divorce Could Affect Your Medical Practice Signs for bikes may have helped avert crash Linda to bike round the Big Apple to raise funds for MS Cyclists "Pedal to the Point" to raise money for multiple sclerosis After 22 years of silence, local company executive to bike in MS ... Multiple Sclerosis Research: Chinese Medicine..Getting DMT is ... Signs for bikes may have helped avert crash Linda to bike round the Big Apple to raise funds for MS Cyclists "Pedal to the Point" to raise money for multiple sclerosis After 22 years of silence, local company executive to bike in MS ...  9 people you need on your medical team Approach may shield patients' immune system Multiple Sclerosis and Vision Problems TOO HIGH TO CARE: Cannabinoids Decrease the Th17 Inflammatory Autoimmune Phenotype. Determinants of cognitive impairment Study: These results corroborate the evidence about the presence and the nature of cognitive impairment in a large sample of MSers. Furthermore, these findings identify significant clinical and demographic determinants of cognitive impairment in a large sample of MSers for the first time. Kelly Osbourne praises her 'unstoppable brother' for his battle with MS Biogen Idec Product Pipeline Will Propel It Higher: with Tysabri sales up due to a program to screen for PML, the approval of Tecfidera, the likely approval of Plegridy (both also for MS) Biogen has been on a roll... MS patients wanted for health study: The Murdock Health Study of Duke Medicine is seeking 100 individuals who have primary progressive multiple sclerosis (PP-MS). Multiple Sclerosis and MRIs Jim Champion, an Army veteran who has suffered from a progressive form of multiple sclerosis for 25 years, speaks about the importance of Illinois' medical marijuana law  Treatment with dalfampridine (AMPYRA) resulted in clinically relevant improvements in walking speed and endurance in MS patients with limited ambulation and helped improve their motor function   Premature immune senescence in children with MS T-cell homeostasis in pediatric multiple sclerosis: Old cells in young patients Retinal periphlebitis is associated with multiple sclerosis severity Comorbidities at multiple sclerosis diagnosis. Objectively Quantified Physical Activity in Persons with Multiple Sclerosis-. Study provide the first data using an objective physical activity measure and a large sample indicating that only a small proportion of persons with MS are achieving adequate amounts of daily exercise Topography of brain sodium accumulation in progressive multiple sclerosis- Sodium accumulation is present in progressive MS patients, more restricted to the motor system in PPMS and more widespread in SPMS. Local brain sodium accumulation appears as a promising marker to monitor patients with progressive MS. Application of the 2010 revised criteria for the diagnosis of multiple sclerosis patients with clinically isolated syndromes. Top Neurologist Murdered, Neuroscientist Husband Accused  High dose thiamine improves fatigue in multiple sclerosis Myelin Peptide Skin Patch Safe, Reduces MS Activity What is Progressive Multifocal Leukoencephalopathy? Kelly Osbourne on Jack Osbourne multiple sclerosis... Lack of insurance cover for MS prevents patient access to new treatments Less spasticity makes you feel better Analysis: When individuals with multiple sclerosis who were treated with AUBAGIO & were using contraception, but became pregnant and followed the clinical program by stopping treatment & flushing the drug out of their systems, they had healthy babies, according to the drug maker’s analysis of several phase II and III trials. Delayed Liver Function Impairment Secondary to Interferon β-1a Use in Multiple Sclerosis. Protein kinase C polymorphisms and vitamin D levels in multiple sclerosis. Olfactory System and Demyelination. Genetic burden in multiple sclerosis families. Retinal periphlebitis is associated with multiple sclerosis severity. How interferon beta proteins bind to cells and activate an immune response Longitudinal Change in Physical Activity and Its Correlates in Relapsing-Remitting Multiple Sclerosis Teriflunomide in relapsing multiple sclerosis: therapeutic utility Multiple sclerosis-like neurological manifestations in a coeliac patient: nothing is as it seems Paroxysmal symptoms in multiple sclerosis masquerading as transient ischaemic attacks Early mitoxantrone-induced cardiotoxicity in secondary progressive multiple sclerosis Subjective Cognitive Impairment: The Next Big Thing?  ACE Inhibitors May Slow Cognitive Decline